THERMAL COAGULATION OF SERUM PROTEINS
نویسندگان
چکیده
منابع مشابه
Thermal coagulation of serum proteins; the effects of iodoacetate, iodoacetamide, and thiol compounds on coagulation.
In the course of studies of the effect of heat on the proteins of human serum it was observed that, at pH 7.4, minute amounts of sodium iodoacetate completely prevented thermal coagulation, while traces of mercaptans markedly enhanced the coagulation. The present paper is an analysis of these observations. The thermal coagulation of a protein, such as egg albumin, has been postulated (1) to con...
متن کاملThermal Coagulation of Serum Proteins I. the Effects of Iodoacetate, Iodoacetamide, and Thiol Compounds on Coagulation*
In the course of studies of the effect of heat on the proteins of human serum it was observed that, at pH 7.4, minute amounts of sodium iodoacetate completely prevented thermal coagulation, while traces of mercaptans markedly enhanced the coagulation. The present paper is an analysis of these observations. The thermal coagulation of a protein, such as egg albumin, has been postulated (1) to con...
متن کاملThermal coagulation of serum proteins. III. The effects of pH and of sulfhydryl reagents on the nature of the coagulum.
In solutions of serum heated at 100” at neutrality, the presence of small amounts of sulfhydryl reagents markedly alters the course of coagulation; iodoacetic acid strongly inhibits the formation of a coagulum, while iodoacetamide, methyl iodoacetate, and p-chloromercuribenzoate accelerate the rate at which a solid gel is obtained (1). The formation of a solid onephase coagulum or gel in a heat...
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Thermal characteristics of egg white proteins (EWP) may differ in the presence of saccharides. Therefore, the influence of saccharides including carboxymethyl cellulose (CMC), pectin, sucrose and maltodextrin and heating time on physicochemical characteristics of EWP as a whole were studied. Investigation of Heat Coagulation Time (HCT), solubility, turbidity and protein secondary structure of h...
متن کاملMercaptan-induced coagulation of proteins.
Part II of this paper will concern the solution of limiting dimensions for micro-meteorites in an atmosphere of constant temperature gradient and in the general case. A critical discussion of the assumptions adopted here will be included as well as some elaboration of the numerical results. * This paper was written as a part of the investigation for United States Naval Ordnance Contract-10449-0...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)51259-5